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XB-MORPHOLINO-17249779
Morpholino Name:
irx2 MO1
Synonyms: MOIrx2
Target mRNA: irx2
Morpholino Type: uncategorized morpholino
Sequence: 5' AGGTAACCCTGAGGATAGGACATGG 3'
Source: Gene Tools LLC
Synonyms: MOIrx2
Target mRNA: irx2
Morpholino Type: uncategorized morpholino
Sequence: 5' AGGTAACCCTGAGGATAGGACATGG 3'
Source: Gene Tools LLC
Target mRNA | tropicalis | laevis.L | laevis.S | ||||
Identities | 25/25 | 25/25 | 25/25 | ||||
genome
MO
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5' CCATGTCCTATCCTCAGGGTTACCT 3' ||||||||||||||||||||||||| 3' GGTACAGGATAGGAGTCCCAATGGA 5' |
5' CCATGTCCTATCCTCAGGGTTACCT 3' ||||||||||||||||||||||||| 3' GGTACAGGATAGGAGTCCCAATGGA 5' |
5' CCATGTCCTATCCTCAGGGTTACCT 3' ||||||||||||||||||||||||| 3' GGTACAGGATAGGAGTCCCAATGGA 5' |
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Genomic Alignments | Position | Identity | Strand | Target | Target mRNA | ||
laevis 10.1 | Chr6S:58514034..58514058 | 25/25 | Antisense | target | irx2.S | ||
Chr6L:71462552..71462576 | 25/25 | Sense | target | irx2.L | |||
Chr4S:25300116..25300140 | 23/25 | Antisense | off-target | irx5.S | |||
Chr4L:34597706..34597730 | 22/25 | Antisense | off-target | irx5.L | tropicalis 10.0 | Chr6:67766824..67766848 | 25/25 | Sense | target | irx2 |
Chr4:42285215..42285239 | 23/25 | Antisense | off-target | irx5 | |||
Chr3:21076452..21076476 | 21/25 | Antisense | off-target | slc6a7 | |||
Publications | |||||||
???morpholino.displaySummary.papersFirst??? |
The Xenopus Irx genes are essential for neural patterning and define the border between prethalamus and thalamus through mutual antagonism with the anterior repressors Fezf and Arx., Dev Biol 2009 |
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???morpholino.displaySummary.papersRecent??? |
The conserved barH-like homeobox-2 gene barhl2 acts downstream of orthodentricle-2 and together with iroquois-3 in establishment of the caudal forebrain signaling center induced by Sonic Hedgehog., Dev Biol 2014 |
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???morpholino.displaySummary.papersAll??? |