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XB-MORPHOLINO-17310728
Morpholino Name:
etv6 MO2
Synonyms: tel1
Target mRNA: etv6
Morpholino Type: translation blocking morpholino (5' UTR)
Sequence: 5' CCTCTGGGAAACAGAAACTTAGCAC 3'
Source: Gene Tools LLC
Synonyms: tel1
Target mRNA: etv6
Morpholino Type: translation blocking morpholino (5' UTR)
Sequence: 5' CCTCTGGGAAACAGAAACTTAGCAC 3'
Source: Gene Tools LLC
Target mRNA | tropicalis | laevis.L | laevis.S | ||||
Identities | 24/25 | 24/25 | 25/25 | ||||
genome
MO
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5' GTGCTAAGTTTTTGTTTCCCAGAGG 3'
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3' CACGATTCAAAGACAAAGGGTCTCC 5' |
5' GTGCTAAGTTTTTGTTTCCCAGAGG 3'
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3' CACGATTCAAAGACAAAGGGTCTCC 5' |
5' GTGCTAAGTTTCTGTTTCCCAGAGG 3' ||||||||||||||||||||||||| 3' CACGATTCAAAGACAAAGGGTCTCC 5' |
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Genomic Alignments | Position | Identity | Strand | Target | Target mRNA | ||
laevis 10.1 | Chr3S:4823605..4823629 | 25/25 | Antisense | target | etv6.S | ||
Chr3L:7174278..7174302 | 24/25 | Antisense | target | etv6.L | |||
Chr4S:118659410..118659434 | 21/25 | Antisense | off-target | XB5772073.S | |||
Chr6S:45348077..45348101 | 21/25 | Sense | off-target | LOC108719987 | tropicalis 10.0 | Chr3:8144148..8144172 | 24/25 | Antisense | target | etv6 |
Publications | |||||||
???morpholino.displaySummary.papersFirst??? |
Tel1/ETV6 specifies blood stem cells through the agency of VEGF signaling., Dev Cell 2010 |
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???morpholino.displaySummary.papersRecent??? |
VEGFA-dependent and -independent pathways synergise to drive Scl expression and initiate programming of the blood stem cell lineage in Xenopus., Development 2013 |
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???morpholino.displaySummary.papersAll??? |