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XB-GRNA-25875084
gRNA Name:
lrp2 gRNA2
Synonyms:
Genomic Target: lrp2
PAM Sequence: GGG
Sequence: 5' AGTAGCAAAGGCCTCCAGTT 3'
Synonyms:
Genomic Target: lrp2
PAM Sequence: GGG
Sequence: 5' AGTAGCAAAGGCCTCCAGTT 3'
Genomic Target | tropicalis | laevis.L | |||||
Identities | 18/20 | 20/20 | |||||
genome
gRNA
|
5' AGCCGGAGGCCTTTGCTACT 3' | | |||||||||||||||| 3' TTGACCTCCGGAAACGATGA 5' |
5' AACTGGAGGCCTTTGCTACT 3' |||||||||||||||||||| 3' TTGACCTCCGGAAACGATGA 5' |
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Genomic Alignments | Position | Identity | Strand | Target | Genomic Target | ||
laevis 10.1 | Chr9_10L:75068540..75068559 | 20/20 | Sense | target | lrp2.L | ||
Chr5L:45702500..45702519 | 17/20 | Sense | off-target | LOC108716675 | |||
Chr3S:77747296..77747315 | 16/20 | Antisense | off-target | grm8.S | |||
Chr6S:103432697..103432716 | 16/20 | Antisense | off-target | nkain3.S | |||
Chr9_10L:24052361..24052380 | 16/20 | Sense | off-target | card14.L | |||
Chr2L:190066883..190066902 | 16/20 | Sense | off-target | LOC121400096 | |||
Chr5S:55918485..55918504 | 16/20 | Antisense | off-target | LOC108717423 | |||
Chr1L:935816..935835 | 16/20 | Sense | off-target | LOC108704869 | |||
Chr8L:84908221..84908240 | 16/20 | Antisense | off-target | LOC108698967 | |||
Chr2S:100921344..100921363 | 19/20 | Antisense | unknown | ||||
Chr7S:36313877..36313896 | 18/20 | Sense | unknown | ||||
Chr9_10S:116862866..116862885 | 17/20 | Antisense | unknown | ||||
Chr3S:125097456..125097475 | 16/20 | Antisense | unknown | ||||
Chr4L:42583226..42583245 | 16/20 | Antisense | unknown | ||||
Chr4L:57847650..57847669 | 16/20 | Antisense | unknown | ||||
Chr4L:67151361..67151380 | 16/20 | Antisense | unknown | ||||
Chr6L:87443696..87443715 | 16/20 | Sense | unknown | ||||
Chr9_10L:78784178..78784197 | 16/20 | Sense | unknown | ||||
Chr5S:59189090..59189109 | 16/20 | Sense | unknown | tropicalis 10.0 | Chr9:68764206..68764225 | 18/20 | Antisense | target | lrp2 |
Publications | |||||||
???morpholino.displaySummary.papersFirst??? |
Neural tube closure requires the endocytic receptor Lrp2 and its functional interaction with intracellular scaffolds., Development 2021 |
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???morpholino.displaySummary.papersRecent??? | |||||||
???morpholino.displaySummary.papersAll??? |