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Summary Expression Phenotypes Gene Literature (4) GO Terms (10) Nucleotides (90) Proteins (41) Interactants (30) Wiki
XB-GENEPAGE-1004949
???displayGene.symbol???:
 siah2

???displayGene.name???: 
siah E3 ubiquitin protein ligase 2

???displayGene.synonyms???
Xsiah-2 , xsiah2 ( Nomenclature history )

???displayGene.geneFunction???
ubiquitin-protein ligase

Protein Function :
E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the ...[+]



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Human Physical (14), Co-citation (16)

Diseases: 


External Links:
 
Gene ID & Location
Xenbase Gene ID XB-GENE-1004950 XB-GENE-1004954
Gene Symbol siah2 siah2.L
Chromosome Chr5 Chr5L
???displayGene.molecues??? X. tropicalis X. laevis.L
Genomic Sequence Version 10.0 Version 10.1
CDS CDS Gene Model CDS Gene Model
Entrez Gene 100124319 373622
Ensembl Gene siah2 (ENSXETG00000035020)
mRNA RefSeq NCBI Nt  More.. RefSeq NCBI Nt  More..
Protein RefSeq  More.. RefSeq Swiss-Prot  More..
Reference Proteome A4IIN1 Q9I8X5
AlphaFold View on AlphaFold View on AlphaFold
???displayGene.genomic??? X. tropicalis X. laevis.L
Genome Browser
(Click image to open in interactive Genome Browser)
Genomic Synteny Xenbase Simple Synteny Genomicus PANTHER
???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
???displayGene.human???
HGNC, Alliance, Monarch, MIM, GeneCards SIAH2 MIM Ensembl, Protein Atlas, Allen Brain Atlas
???displayGene.mouse???
MGI, Alliance Siah2 MGI, IMPC Ensembl, Allen Brain Atlas, MGI
rat
RGD, Alliance Siah2 Ensembl
???displayGene.zebrafish???
chicken
GEISHA SIAH2 Ensembl
fruit fly
Publications
First Misexpression of Xsiah-2 induces a small eye phenotype in Xenopus., Mech Dev 2001     
Most Recent Role of the hypoxia response pathway in lens formation during embryonic development of Xenopus laevis., FEBS Open Bio 2013     
All ???displayGene.papersAll???
Functional Ontologies X. tropicalis X. laevis.L
GO 8 terms 12 terms 0 terms
KEGG Pathways
KOG [R] Zn finger protein (alt_id KOG:3002)
Reagents X. tropicalis X. laevis.L
CRISPRscan Tracks siah2 siah2.L
ORFs siah2 ORF1
Clones Horizon Horizon
Plasmids Addgene.org


Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info