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Summary Expression Phenotypes Gene Literature (293) GO Terms (11) Nucleotides (233) Proteins (58) Interactants (1453) Wiki
XB-GENEPAGE-479801
???displayGene.symbol???:
 twist1

???displayGene.name???: 
twist family bHLH transcription factor 1

???displayGene.synonyms???
twist , twist1-a , twist1-b , X-twi , Xtwi , Xtwist [+] ( Nomenclature history )

???displayGene.geneFunction???
transcription factor

Protein Function :
Probable transcription factor, which may be involved, with other proteins, in establishing the pattern of cell type-specific gene expression in mesodermal cell subgroups.



???displayGene.geneInteractants???
Human Physical (22), Co-citation (1431)

Diseases: 


Disease Ontology:
craniosynostosis [+]

MIM:
SWEENEY-COX SYNDROME; SWCOS [+]

External Links:
1/10
 
Gene ID & Location
Xenbase Gene ID XB-GENE-479802 XB-GENE-6255840 XB-GENE-865309
Gene Symbol twist1 twist1.L twist1.S
Chromosome Chr6 Chr6L Chr6S
???displayGene.molecues??? X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 10.1 Version 10.1
CDS CDS Gene Model CDS Gene Model CDS Gene Model
Entrez Gene 395054 100036981 378698
Ensembl Gene twist1 (ENSXETG00000025630)
mRNA RefSeq NCBI Nt  More.. RefSeq NCBI Nt  More.. RefSeq NCBI Nt  More..
Protein RefSeq  More.. RefSeq  More.. RefSeq Swiss-Prot  More..
Reference Proteome Q9PUL7 A1L2X6 P13903
AlphaFold View on AlphaFold View on AlphaFold View on AlphaFold
???displayGene.genomic??? X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in interactive Genome Browser)
Genomic Synteny Xenbase Simple Synteny Genomicus PANTHER
???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
???displayGene.human???
HGNC, Alliance, Monarch, MIM, GeneCards TWIST1 MIM Ensembl, Protein Atlas, Allen Brain Atlas
???displayGene.mouse???
MGI, Alliance Twist1 MGI, IMPC Ensembl, Allen Brain Atlas, MGI
rat
RGD, Alliance Twist1 Ensembl
???displayGene.zebrafish???
ZFIN, Alliance ZFIN, Alliance twist1b twist1a  ZFIN Ensembl
chicken
GEISHA TWIST1 Ensembl
fruit fly
Publications
First Facile cruciform formation by an (A-T)34 sequence from a Xenopus globin gene., J Mol Biol 1985  
Most Recent Histological and gene-expression analyses of pyloric sphincter formation during stomach metamorphosis in Xenopus laevis., Dev Biol 2024  
All ???displayGene.papersAll??? 66 ???displayGene.morpholinoPapers??? 15 ???displayGene.omimPapers??? 32 ???displayGene.disOntPapers???
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 8 terms 2 terms 5 terms
KEGG Pathways
KOG [K] Transcription factor TWIST
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks twist1 twist1.L twist1.S
Morpholinos twist1 MO1, twist1 MO2, twist1 MO3 twist1 MO1, twist1 MO2, twist1 MO3 twist1 MO1, twist1 MO2, twist1 MO3
ORFs twist1 ORF1 twist1.L ORF1 twist1.S ORF1
Clones EXRC, Horizon Horizon Horizon
Plasmids Addgene.org Addgene.org


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