The gtf2i gene encodes a transcription factor protein localized to the nucleus. This protein binds DNA through its i-repeat domains and regulates the expression of target genes. It is involved in embry...[+]

The gtf2i gene encodes a transcription factor protein localized to the nucleus. This protein binds DNA through its i-repeat domains and regulates the expression of target genes. It is involved in embryonic development, particularly in the formation of the cranial neural crest and branchial arches. Expression is also detected in the developing eye, otic vesicle, brain, and spinal cord. [-]

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