The srf gene encodes a mads-box transcription factor protein localized in the nucleus. It binds serum response elements in DNA promoter regions. This protein is involved in regulating genes for immedia...[+]

The srf gene encodes a mads-box transcription factor protein localized in the nucleus. It binds serum response elements in DNA promoter regions. This protein is involved in regulating genes for immediate-early response and muscle differentiation. Expression is documented in cranial neural crest cells, mesoderm, developing eye, branchial arches, somites, and tailbud. Its function includes a role in controlling actin dynamics and cytoskeleton organization during gastrulation movements. [-]

ClinVar, ClinGen, MalaCards, KEGG Disease, DECIPHER, COSMIC, MARRVEL, GTR, DisGeNET, dbVAR, GHR, gnomAD