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Summary Expression Phenotypes Gene Literature (108) GO Terms (16) Nucleotides (62) Proteins (34) Interactants (83) Wiki
XB-GENEPAGE-982936
???displayGene.symbol???:
 kcnb1

???displayGene.name???: 
potassium channel, voltage gated Shab related subfamily B, member 1

???displayGene.synonyms???
drk1 , kv2.1 , LOC108700878 ( Nomenclature history )

???displayGene.geneFunction???
Voltage-gated K+ channel KCNB/KCNC

Protein Function :



???displayGene.geneInteractants???
Human Physical (1), Co-citation (82)

Diseases: 


Disease Ontology:
developmental and epileptic encephalopathy 26

MIM:
DEVELOPMENTAL AND EPILEPTIC ENCEPHALOPATHY 26; DEE26

External Links:
 
Gene ID & Location
Xenbase Gene ID XB-GENE-982937 XB-GENE-17336197 XB-GENE-982940
Gene Symbol kcnb1 kcnb1.L kcnb1.S
Chromosome Chr10 Chr9_10L Chr9_10S
???displayGene.molecues??? X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 10.1 Version 10.1
CDS CDS Gene Model CDS Gene Model CDS Gene Model
Entrez Gene 100489405 108700878 378535
Ensembl Gene kcnb1 (ENSXETG00000016003)
mRNA NCBI Nt RefSeq RefSeq RefSeq RefSeq  More..
Protein NCBI Protein TrEMBL RefSeq RefSeq RefSeq RefSeq  More..
Reference Proteome A0A803JWF6
AlphaFold View on AlphaFold View on AlphaFold
???displayGene.genomic??? X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in interactive Genome Browser)
Genomic Synteny Xenbase Simple Synteny Genomicus PANTHER
???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
???displayGene.human???
HGNC, Alliance, Monarch, MIM, GeneCards KCNB1 MIM Ensembl, Protein Atlas, Allen Brain Atlas
???displayGene.mouse???
MGI, Alliance Kcnb1 MGI, IMPC Ensembl, Allen Brain Atlas, MGI
rat
RGD, Alliance Kcnb1 Ensembl
???displayGene.zebrafish???
kcnb1  Ensembl
chicken
GEISHA KCNB1 Ensembl
fruit fly
Publications
First A novel potassium channel with delayed rectifier properties isolated from rat brain by expression cloning., Nature 1989  
Most Recent Mono-allelic KCNB2 variants lead to a neurodevelopmental syndrome caused by altered channel inactivation., Am J Hum Genet 2024  
All ???displayGene.papersAll??? 2 ???displayGene.omimPapers??? 3 ???displayGene.disOntPapers???
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 12 terms 0 terms 12 terms
KEGG Pathways
KOG [P] Voltage-gated K+ channel KCNB/KCNC
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks kcnb1 kcnb1.L kcnb1.S
Clones Horizon Horizon Horizon
Plasmids Addgene.org Addgene.org


Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info