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Summary Expression Phenotypes Gene Literature (96) GO Terms (7) Nucleotides (391) Proteins (60) Interactants (364) Wiki
XB-GENEPAGE-955797
???displayGene.symbol???:
 gjb2

???displayGene.name???: 
gap junction protein beta 2

???displayGene.synonyms???
connexin 26 , connexin-26 , cx26 , cx29 , dfna3 , dfna3a [+] ( Nomenclature history )

???displayGene.geneFunction???
connexon channel component

Protein Function :
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.



???displayGene.geneInteractants???
Human Physical (49), Co-citation (315)

Diseases: 


Disease Ontology:
X-linked deafness 2 [+]

MIM:
VOHWINKEL SYNDROME; VOWNKL [+]

External Links:
1/2
 
Gene ID & Location
Xenbase Gene ID XB-GENE-955798 XB-GENE-955804 XB-GENE-17336902
Gene Symbol gjb2 gjb2.L gjb2.S
Chromosome Chr2 Chr2L Chr2S
???displayGene.molecues??? X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 10.1 Version 10.1
CDS CDS Gene Model CDS Gene Model CDS Gene Model
Entrez Gene 549738 380170 108709975
Ensembl Gene gjb2 (ENSXETG00000026112)
mRNA RefSeq NCBI Nt  More.. RefSeq NCBI Nt  More.. NCBI Nt
Protein RefSeq  More.. RefSeq  More.. NCBI Protein TrEMBL
Reference Proteome Q28ED4 Q7ZYG3 A0A1L8HAU1
AlphaFold View on AlphaFold View on AlphaFold View on AlphaFold
???displayGene.genomic??? X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in interactive Genome Browser)
Genomic Synteny Xenbase Simple Synteny Genomicus PANTHER
???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: gjb2.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
???displayGene.human???
HGNC, Alliance, Monarch, MIM, GeneCards GJB2 MIM Ensembl, Protein Atlas, Allen Brain Atlas
???displayGene.mouse???
MGI, Alliance Gjb2 MGI, IMPC Ensembl, Allen Brain Atlas, MGI
rat
RGD, Alliance Gjb2 Ensembl
???displayGene.zebrafish???
gjb1b  Ensembl
chicken
GEISHA GJB2 Ensembl
fruit fly
Publications
First Molecular cloning and characterization of a new member of the gap junction gene family, connexin-31., J Biol Chem 1991  
Most Recent Molecular and cellular basis of sodium sensing in Drosophila labellum., iScience 2024     
All ???displayGene.papersAll??? 2 ???displayGene.morpholinoPapers??? 6 ???displayGene.omimPapers??? 14 ???displayGene.disOntPapers???
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 8 terms 5 terms 5 terms
KEGG Pathways
KOG
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks gjb2 gjb2.L gjb2.S
ORFs gjb2.L ORF1
Clones Horizon EXRC, Horizon Horizon
Plasmids Addgene.org Addgene.org


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