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XB-GENEPAGE-920721
???displayGene.symbol???: lmna
???displayGene.name???: lamin A/C
???displayGene.synonyms???
lamin a
,
Lamin-A
,
LOC108700617
(
???displayGene.geneFunction??? nucleoskeletal protein Protein Function :
Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also inter...[+]
???displayGene.geneInteractants???
Human Physical (302), Co-citation (262)
Diseases: Disease Ontology: autosomal dominant Emery-Dreifuss muscular dystrophy 2
MIM:
HEART-HAND SYNDROME, SLOVENIAN TYPE
External Links:
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Gene ID & Location |
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Xenbase Gene ID | XB-GENE-920722 | XB-GENE-920728 | XB-GENE-17342018 | |||||||||
Gene Symbol | lmna | lmna.L | lmna.S | |||||||||
Chromosome | Chr8 | Chr8L | Chr8S | |||||||||
???displayGene.molecues??? | X. tropicalis | X. laevis.L | X. laevis.S | |||||||||
Genomic Sequence | Version 10.0 | Version 10.1 | Version 10.1 | |||||||||
CDS | CDS Gene Model | CDS Gene Model | CDS Gene Model | |||||||||
Entrez Gene | 733973 | 373673 | 108700617 | |||||||||
Ensembl Gene | lmna (ENSXETG00000024161) | |||||||||||
mRNA |
RefSeq
NCBI Nt
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RefSeq NCBI Nt | RefSeq | |||||||||
Protein |
RefSeq
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RefSeq
Swiss-Prot
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RefSeq | |||||||||
Reference Proteome | Q28BY8 | P11048 | ||||||||||
AlphaFold | View on AlphaFold | View on AlphaFold | ||||||||||
???displayGene.genomic??? | X. tropicalis | X. laevis.L | X. laevis.S | |||||||||
Genome Browser (Click image to open in interactive Genome Browser) |
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Genomic Synteny | Xenbase Simple Synteny Genomicus PANTHER | |||||||||||
???displayGene.expression??? | Development Stages Embryonic Tissues Adult Tissues | |||||||||||
Summary for
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More Information |
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Proteomics | X. tropicalis | X. laevis.L | X. laevis.S | |||||||||
Embryonic Protein Expression | Stage profile: lmna.L | Stage profile: lmna.S | ||||||||||
Orthology |
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???displayGene.human??? |
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???displayGene.mouse??? |
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rat |
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???displayGene.zebrafish??? |
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chicken |
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fruit fly |
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Publications | ||||||||||||
First |
Differential expression of nuclear lamin proteins during chicken development., J Cell Biol 1987 |
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Most Recent |
Amphibian mast cells serve as barriers to chytrid fungus infections., Elife 2024 |
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All | ???displayGene.papersAll??? 2 ???displayGene.morpholinoPapers??? 3 ???displayGene.omimPapers??? 4 ???displayGene.disOntPapers??? | |||||||||||
Functional Ontologies | X. tropicalis | X. laevis.L | X. laevis.S | |||||||||
GO | 5 terms | 11 terms | 0 terms | |||||||||
KEGG Pathways | Apoptosis | Apoptosis | ||||||||||
KOG |
[DY] Nuclear envelope protein lamin, intermediate filament superfamily
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Reagents | X. tropicalis | X. laevis.L | X. laevis.S | |||||||||
CRISPRscan Tracks | lmna.L | |||||||||||
Guide RNAs | lmna gRNA1 | lmna gRNA1 | ||||||||||
Mutants | Xtr.lmnaemHorb | |||||||||||
Antibodies | Lmna Ab1, Lmna Ab2, Lmnb2/3 Ab5 | Lmna Ab1, Lmna Ab2, Lmnb2/3 Ab5 | Lmna Ab2, Lmnb2/3 Ab5 | |||||||||
Clones | Horizon | Horizon | Horizon | |||||||||
Plasmids | Addgene.org | Addgene.org |
Symbol legend: Blast sequence View sequence Literature or expression images Hover cursor for info