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XB-GENEPAGE-5810263
???displayGene.symbol???: tpx2
???displayGene.name???: TPX2, microtubule-associated
???displayGene.synonyms???
dil-2
,
dil2
,
hctp4
,
repp86
,
tpx2-a
,
tpx2-b
[+]
(
???displayGene.geneFunction??? Immunoglobin and related proteins Protein Function :
Spindle assembly factor. Required for normal assembly of mitotic spindles. Mediates the binding kif15 and aurka to spindle microtubules. Required for targeting kif15 to microtubule minus ends. Activate...[+]
???displayGene.geneInteractants???
Human Physical (24), Co-citation (375)
Diseases: Disease Ontology: prostate cancer
MIM:
PROSTATE CANCER
External Links:
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Gene ID & Location |
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Xenbase Gene ID | XB-GENE-5810264 | XB-GENE-6251919 | XB-GENE-6255926 | |||||||||
Gene Symbol | tpx2 | tpx2.L | tpx2.S | |||||||||
Chromosome | Chr10 | Chr9_10L | Chr9_10S | |||||||||
???displayGene.molecues??? | X. tropicalis | X. laevis.L | X. laevis.S | |||||||||
Genomic Sequence | Version 10.0 | Version 10.1 | Version 10.1 | |||||||||
CDS | CDS Gene Model | CDS Gene Model | CDS Gene Model | |||||||||
Entrez Gene | 100124787 | 398174 | 446586 | |||||||||
Ensembl Gene | tpx2 (ENSXETG00000002548) | |||||||||||
mRNA |
RefSeq
NCBI Nt
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RefSeq
NCBI Nt
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RefSeq
RefSeq
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Protein |
RefSeq
Swiss-Prot
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RefSeq
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RefSeq
Swiss-Prot
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Reference Proteome | A4IH24 | A0A8J0TJ15 | Q6DDV8 | |||||||||
AlphaFold | View on AlphaFold | View on AlphaFold | View on AlphaFold | |||||||||
???displayGene.genomic??? | X. tropicalis | X. laevis.L | X. laevis.S | |||||||||
Genome Browser (Click image to open in interactive Genome Browser) |
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Genomic Synteny | Xenbase Simple Synteny Genomicus PANTHER | |||||||||||
???displayGene.expression??? | Development Stages Embryonic Tissues Adult Tissues | |||||||||||
Summary for
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More Information |
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Orthology |
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???displayGene.human??? |
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???displayGene.mouse??? |
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rat |
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???displayGene.zebrafish??? |
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chicken |
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fruit fly |
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Publications | ||||||||||||
First |
Localization of the kinesin-like protein Xklp2 to spindle poles requires a leucine zipper, a microtubule-associated protein, and dynein., J Cell Biol 1998 |
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Most Recent |
Exploring the clinical significance of TPX2 in pancreatic cancer: from biomarker to immunotherapy., Naunyn Schmiedebergs Arch Pharmacol 2024 |
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All | ???displayGene.papersAll??? 2 ???displayGene.morpholinoPapers??? 4 ???displayGene.omimPapers??? 11 ???displayGene.disOntPapers??? | |||||||||||
Functional Ontologies | X. tropicalis | X. laevis.L | X. laevis.S | |||||||||
GO | 7 terms | 16 terms | 8 terms | |||||||||
KEGG Pathways | ||||||||||||
KOG |
[RP] FOG: Immunoglobin and related proteins
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Reagents | X. tropicalis | X. laevis.L | X. laevis.S | |||||||||
CRISPRscan Tracks | tpx2.L | tpx2.S | ||||||||||
Morpholinos | tpx2 MO1 | |||||||||||
ORFs | tpx2 ORF1 | tpx2.S ORF1 | ||||||||||
Clones | Horizon | Horizon | Horizon | |||||||||
Plasmids | Addgene.org | Addgene.org |
Symbol legend: Blast sequence View sequence Literature or expression images Hover cursor for info