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XB-GENEPAGE-1004949
???displayGene.symbol???: siah2
???displayGene.name???: siah E3 ubiquitin protein ligase 2
???displayGene.synonyms???
Xsiah-2
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xsiah2
(
???displayGene.geneFunction??? ubiquitin-protein ligase Protein Function :
E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the ...[+]
???displayGene.geneInteractants???
Human Physical (14), Co-citation (16)
Diseases: External Links:
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Gene ID & Location |
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Xenbase Gene ID | XB-GENE-1004950 | XB-GENE-1004954 | ||||||||||
Gene Symbol | siah2 | siah2.L | ||||||||||
Chromosome | Chr5 | Chr5L | ||||||||||
???displayGene.molecues??? | X. tropicalis | X. laevis.L | ||||||||||
Genomic Sequence | Version 10.0 | Version 10.1 | ||||||||||
CDS | CDS Gene Model | CDS Gene Model | ||||||||||
Entrez Gene | 100124319 | 373622 | ||||||||||
Ensembl Gene | siah2 (ENSXETG00000035020) | |||||||||||
mRNA |
RefSeq
NCBI Nt
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RefSeq
NCBI Nt
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Protein |
RefSeq
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RefSeq
Swiss-Prot
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Reference Proteome | A4IIN1 | Q9I8X5 | ||||||||||
AlphaFold | View on AlphaFold | View on AlphaFold | ||||||||||
???displayGene.genomic??? | X. tropicalis | X. laevis.L | ||||||||||
Genome Browser (Click image to open in interactive Genome Browser) |
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Genomic Synteny | Xenbase Simple Synteny Genomicus PANTHER | |||||||||||
???displayGene.expression??? | Development Stages Embryonic Tissues Adult Tissues | |||||||||||
Summary for
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More Information |
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Orthology |
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???displayGene.human??? |
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???displayGene.mouse??? |
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rat |
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???displayGene.zebrafish??? |
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chicken |
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fruit fly |
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Publications | ||||||||||||
First |
Misexpression of Xsiah-2 induces a small eye phenotype in Xenopus., Mech Dev 2001 |
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Most Recent |
Role of the hypoxia response pathway in lens formation during embryonic development of Xenopus laevis., FEBS Open Bio 2013 |
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All | ???displayGene.papersAll??? | |||||||||||
Functional Ontologies | X. tropicalis | X. laevis.L | ||||||||||
GO | 8 terms | 12 terms | 0 terms | |||||||||
KEGG Pathways | ||||||||||||
KOG |
[R] Zn finger protein (alt_id KOG:3002)
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Reagents | X. tropicalis | X. laevis.L | ||||||||||
CRISPRscan Tracks | siah2 | siah2.L | ||||||||||
ORFs | siah2 ORF1 | |||||||||||
Clones | Horizon | Horizon | ||||||||||
Plasmids | Addgene.org |
Symbol legend: Blast sequence View sequence Literature or expression images Hover cursor for info