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Summary Expression Phenotypes Gene Literature (13) GO Terms (3) Nucleotides (141) Proteins (47) Interactants (374) Wiki
XB-GENEPAGE-6033924
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 dot1l

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DOT1-like histone H3K79 methyltransferase

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( Nomenclature history )

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Putative protein methyltransferase involved in meiosis and transcriptional silencing (Dot1)

Protein Function :
Histone methyltransferase that specifically trimethylates histone H3 to form H3K79me3. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle...[+]


InterPro :
SAM-dependent MTases, H3-K79 meTrfase, DOT1 dom, A-D-PHexomutase CS, [+]

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Diseases: 


External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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