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Summary Expression Phenotypes Gene Literature (102) GO Terms (6) Nucleotides (574) Proteins (69) Interactants (356) Wiki
XB-GENEPAGE-974719
???displayGene.symbol???:
 cdc6

???displayGene.name???: 
cell division cycle 6

???displayGene.synonyms???
xcdc6 ( Nomenclature history )

???displayGene.geneFunction???
Pre-initiation complex, subunit CDC6, AAA+ superfamily ATPase

Protein Function :
Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated.



???displayGene.geneInteractants???
Human Physical (39), Co-citation (317)

Diseases: 


Disease Ontology:
Meier-Gorlin syndrome

MIM:
MEIER-GORLIN SYNDROME 5; MGORS5

External Links:
 
Gene ID & Location
Xenbase Gene ID XB-GENE-974720 XB-GENE-974724 XB-GENE-17346530
Gene Symbol cdc6 cdc6.L cdc6.S
Chromosome Chr10 Chr9_10L Chr9_10S
???displayGene.molecues??? X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 10.1 Version 10.1
CDS CDS Gene Model CDS Gene Model CDS Gene Model
Entrez Gene 493356 403388 398082
Ensembl Gene wipf2 (ENSXETG00000024394)
mRNA RefSeq NCBI Nt  More.. RefSeq NCBI Nt  More.. RefSeq NCBI Nt  More..
Protein RefSeq  More.. RefSeq RefSeq  More.. RefSeq  More..
Reference Proteome Q66JL2 Q6IP89 P79946
AlphaFold View on AlphaFold View on AlphaFold View on AlphaFold
???displayGene.genomic??? X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in interactive Genome Browser)
Genomic Synteny Xenbase Simple Synteny Genomicus PANTHER
???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: cdc6.L Stage profile: cdc6.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
???displayGene.human???
HGNC, Alliance, Monarch, MIM, GeneCards CDC6 MIM Ensembl, Protein Atlas, Allen Brain Atlas
???displayGene.mouse???
MGI, Alliance Cdc6 MGI, IMPC Ensembl, Allen Brain Atlas, MGI
rat
RGD, Alliance Cdc6 Ensembl
???displayGene.zebrafish???
ZFIN, Alliance cdc6  ZFIN Ensembl
chicken
GEISHA CDC6 Ensembl
fruit fly
FLYBASE Cdc6 Ensembl
Publications
First Replication origins in eukaroytes., Curr Opin Genet Dev 1996  
Most Recent A transphyletic study of metazoan β-catenin protein complexes., Zoological Lett 2024     
All ???displayGene.papersAll??? 1 ???displayGene.disOntPapers???
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 4 terms 6 terms 6 terms
KEGG Pathways Cell cycle Cell cycle Cell cycle
KOG [LD] Pre-initiation complex, subunit CDC6, AAA+ superfamily ATPase
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks cdc6.L cdc6.S
Antibodies Cdc6 Ab2, Cdc6 Ab1, Cdc6 Ab3 Cdc6 Ab2, Cdc6 Ab1, Cdc6 Ab3
Morpholinos cdc6 MO1
ORFs cdc6 ORF1 cdc6.L ORF1 Xcdc6 ORF1
Clones Horizon Horizon Horizon
Plasmids Addgene.org Addgene.org


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