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XB-GENEPAGE-479317
???displayGene.symbol???: notch1
???displayGene.name???: notch 1 receptor
???displayGene.synonyms???
notch
,
notch-1
,
xnotch
,
x-notch-1
,
xnotch1
,
xotch
[+]
(
???displayGene.geneFunction??? signal transduction, receptor for delta class ligands Protein Function :
Functions as a receptor for membrane-bound ligands Jagged-1 (JAG1), Jagged-2 (JAG2) and Delta-1 (DLL1) to regulate cell-fate determination. Upon ligand activation through the released notch intracellul...[+]
???displayGene.geneInteractants???
Human Physical (16), Co-citation (1840)
Diseases: Disease Ontology: aortic valve stenosis
MIM:
ADAMS-OLIVER SYNDROME 5; AOS5
External Links:
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Gene ID & Location |
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Xenbase Gene ID | XB-GENE-479318 | XB-GENE-17342057 | XB-GENE-865261 | |||||||||
Gene Symbol | notch1 | notch1.L | notch1.S | |||||||||
Chromosome | Chr8 | Chr8L | Chr8S | |||||||||
???displayGene.molecues??? | X. tropicalis | X. laevis.L | X. laevis.S | |||||||||
Genomic Sequence | Version 10.0 | Version 10.1 | Version 10.1 | |||||||||
CDS | CDS Gene Model | CDS Gene Model | CDS Gene Model | |||||||||
Entrez Gene | 100037842 | 108698191 | 394367 | |||||||||
Ensembl Gene | notch1 (ENSXETG00000000757) | |||||||||||
mRNA |
RefSeq
NCBI Nt
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NCBI Nt | RefSeq NCBI Nt | |||||||||
Protein |
RefSeq
Swiss-Prot
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NCBI Protein
TrEMBL
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RefSeq
Swiss-Prot
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Reference Proteome | A2RUV0 | A0A1L8F627 | P21783 | |||||||||
AlphaFold | View on AlphaFold | View on AlphaFold | View on AlphaFold | |||||||||
???displayGene.genomic??? | X. tropicalis | X. laevis.L | X. laevis.S | |||||||||
Genome Browser (Click image to open in interactive Genome Browser) |
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Genomic Synteny | Xenbase Simple Synteny Genomicus PANTHER | |||||||||||
???displayGene.expression??? | Development Stages Embryonic Tissues Adult Tissues | |||||||||||
Summary for
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More Information |
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Proteomics | X. tropicalis | X. laevis.L | X. laevis.S | |||||||||
Embryonic Protein Expression | Stage profile: notch1.S | |||||||||||
Orthology |
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???displayGene.human??? |
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???displayGene.mouse??? |
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rat |
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???displayGene.zebrafish??? |
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chicken |
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fruit fly |
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Publications | ||||||||||||
First |
Cell patterning in pigment-chimeric eyes in Xenopus: germinal transplants and their contributions to growth of the pigmented retinal epithelium., Proc Natl Acad Sci U S A 1987 |
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Most Recent |
Nodal and churchill1 position the expression of a notch ligand during Xenopus germ layer segregation., Life Sci Alliance null |
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All | ???displayGene.papersAll??? 54 ???displayGene.morpholinoPapers??? 6 ???displayGene.omimPapers??? 19 ???displayGene.disOntPapers??? | |||||||||||
Functional Ontologies | X. tropicalis | X. laevis.L | X. laevis.S | |||||||||
GO | 10 terms | 9 terms | 11 terms | |||||||||
KEGG Pathways | Notch signaling pathway | Notch signaling pathway | Notch signaling pathway | |||||||||
KOG |
[O] 26S proteasome regulatory complex, subunit PSMD10
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Reagents | X. tropicalis | X. laevis.L | X. laevis.S | |||||||||
CRISPRscan Tracks | notch1 | notch1.L | notch1.S | |||||||||
Guide RNAs | notch1 gRNA1 | notch1 gRNA1 | notch1 gRNA1 | |||||||||
Antibodies | Notch1 AB1 | Notch1 AB1 | Notch1 AB1 | |||||||||
Morpholinos | notch1 MO1 | notch1 MO1 | ||||||||||
Clones | Horizon | Horizon | EXRC, Horizon | |||||||||
Plasmids | Addgene.org | Addgene.org |
Symbol legend: Blast sequence View sequence Literature or expression images Hover cursor for info