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Summary Expression Phenotypes Gene Literature (15) GO Terms (11) Nucleotides (278) Proteins (43) Interactants (385) Wiki
XB-GENEPAGE-976426
???displayGene.symbol???:
 gpc4

???displayGene.name???: 
glypican 4

???displayGene.synonyms???
glypican-4 , K-glypican , knypek , Xgly4 ( Nomenclature history )

???displayGene.geneFunction???
heparin sulfate cell surface proteoglycan

Protein Function :
Cell surface proteoglycan that bears heparan sulfate.



???displayGene.geneInteractants???
Human Physical (16), Co-citation (369)

Diseases: 


Disease Ontology:
nephroblastoma [+]

MIM:
SIMPSON-GOLABI-BEHMEL SYNDROME, TYPE 1; SGBS1 [+]

External Links:
 
Gene ID & Location
Xenbase Gene ID XB-GENE-976427 XB-GENE-976431 XB-GENE-17337230
Gene Symbol gpc4 gpc4.L gpc4.S
Chromosome Chr8 Chr8L Chr8S
???displayGene.molecues??? X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 10.1 Version 10.1
CDS CDS Gene Model CDS Gene Model CDS Gene Model
Entrez Gene 100126682 399356 108700175
Ensembl Gene gpc4 (ENSXETG00000005400)
mRNA NCBI Nt NCBI Nt RefSeq NCBI Nt  More.. NCBI Nt
Protein NCBI Protein RefSeq  More.. NCBI Protein TrEMBL
Reference Proteome F7CR54 Q5EAV3 A0A1L8F395
AlphaFold View on AlphaFold View on AlphaFold View on AlphaFold
???displayGene.genomic??? X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in interactive Genome Browser)
Genomic Synteny Xenbase Simple Synteny Genomicus PANTHER
???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: gpc4.L Stage profile: gpc4.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
???displayGene.human???
HGNC, Alliance, Monarch, MIM, GeneCards GPC4 MIM Ensembl, Protein Atlas, Allen Brain Atlas
???displayGene.mouse???
MGI, Alliance Gpc4 MGI, IMPC Ensembl, Allen Brain Atlas, MGI
rat
RGD, Alliance Gpc4 Ensembl
???displayGene.zebrafish???
ZFIN, Alliance gpc4  ZFIN Ensembl
chicken
GEISHA GPC4 Ensembl
fruit fly
Publications
First Identification of tissues and patterning events required for distinct steps in early migration of zebrafish primordial germ cells., Development 1999  
Most Recent Cell-cell contact landscapes in Xenopus gastrula tissues., Proc Natl Acad Sci U S A 2021     
All ???displayGene.papersAll??? 4 ???displayGene.morpholinoPapers???
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 4 terms 13 terms 11 terms
KEGG Pathways Wnt signaling pathway Wnt signaling pathway Wnt signaling pathway
KOG [T] Heparin sulfate cell surface proteoglycan
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks gpc4 gpc4.L gpc4.S
Morpholinos gpc4 MO2, gpc4 MO5 gpc4 MO1, gpc4 MO2, gpc4 MO5 gpc4 MO2, gpc4 MO5
ORFs gpc4.L ORF1
Clones Horizon Horizon Horizon
Plasmids Addgene.org Addgene.org


Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info