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Summary Expression Phenotypes Gene Literature (18) GO Terms (5) Nucleotides (65) Proteins (40) Interactants (199) Wiki
XB-GENEPAGE-1221136
???displayGene.symbol???:
 invs

???displayGene.name???: 
inversin

???displayGene.synonyms???
inversin , invs-a , invs-b , nephrocystin-2 , NPH2 , NPHP2 [+] ( Nomenclature history )

???displayGene.geneFunction???
multiple ankyrin domains and two IQ calmodulin-binding domains: functions in cilia formation and left-right axis establishment

Protein Function :
Required for normal renal development and establishment of left-right axis. Probably acts as a molecular switch between different Wnt signaling pathways. Inhibits the canonical Wnt pathway by targeting...[+]


InterPro :
CNKSR2, SAM, PDZ, PDZ sf, [+]

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
Senior-Loken syndrome [+]

External Links:
 
???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info