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Summary Expression Phenotypes Gene Literature (40) GO Terms (4) Nucleotides (160) Proteins (36) Interactants (138) Wiki
XB-GENEPAGE-1010856
???displayGene.symbol???:
 bub1b

???displayGene.name???: 
BUB1B, mitotic checkpoint serine/threonine kinase

???displayGene.synonyms???
bubr1 ( Nomenclature history )

???displayGene.geneFunction???
Mitotic checkpoint serine/threonine protein kinase

Protein Function :



???displayGene.geneInteractants???
Human Physical (48), Co-citation (90)

Diseases: 


Disease Ontology:
colorectal cancer [+]

MIM:
PREMATURE CHROMATID SEPARATION TRAIT; PCS [+]

External Links:
 
Gene ID & Location
Xenbase Gene ID XB-GENE-1010857 XB-GENE-1010862
Gene Symbol bub1b bub1b.L
Chromosome Chr8 Chr8L
???displayGene.molecues??? X. tropicalis X. laevis.L
Genomic Sequence Version 10.0 Version 10.1
CDS CDS Gene Model CDS Gene Model
Entrez Gene 100125106 378923
Ensembl Gene bub1b (ENSXETG00000000287)
mRNA NCBI Nt NCBI Nt  More.. RefSeq NCBI Nt  More..
Protein NCBI Protein NCBI Protein  More.. RefSeq  More..
Reference Proteome F6TGK2 Q8JGT8
AlphaFold View on AlphaFold View on AlphaFold
???displayGene.genomic??? X. tropicalis X. laevis.L
Genome Browser
(Click image to open in interactive Genome Browser)
Genomic Synteny Xenbase Simple Synteny Genomicus PANTHER
???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:
Proteomics X. tropicalis X. laevis.L
Embryonic Protein Expression Stage profile: bub1b.L
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
???displayGene.human???
HGNC, Alliance, Monarch, MIM, GeneCards BUB1B MIM Ensembl, Protein Atlas, Allen Brain Atlas
???displayGene.mouse???
MGI, Alliance Bub1b MGI, IMPC Ensembl, Allen Brain Atlas, MGI
rat
RGD, Alliance Bub1b Ensembl
???displayGene.zebrafish???
chicken
GEISHA BUB1B Ensembl
fruit fly
Publications
First CENP-E as an essential component of the mitotic checkpoint in vitro., Cell 2000  
Most Recent The Borealin dimerization domain interacts with Sgo1 to drive Aurora B-mediated spindle assembly., Mol Biol Cell 2020     
All ???displayGene.papersAll??? 1 ???displayGene.omimPapers??? 1 ???displayGene.disOntPapers???
Functional Ontologies X. tropicalis X. laevis.L
GO 4 terms 4 terms 0 terms
KEGG Pathways Cell cycle Cell cycle
KOG [D] Mitotic checkpoint serine/threonine protein kinase
Reagents X. tropicalis X. laevis.L
CRISPRscan Tracks bub1b bub1b.L
ORFs bub1b ORF1
Clones Horizon Horizon
Plasmids Addgene.org


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