The suclg2 protein is a mitochondrial enzyme functioning as a succinate-CoA ligase subunit involved in the citric acid cycle, catalyzing the conversion of succinate to succinyl-CoA coupled to ATP or GT...[+]

The suclg2 protein is a mitochondrial enzyme functioning as a succinate-CoA ligase subunit involved in the citric acid cycle, catalyzing the conversion of succinate to succinyl-CoA coupled to ATP or GTP synthesis from ADP or GDP and inorganic phosphate. It localizes to the mitochondrial matrix. Expression is documented in neural crest cells, cranial ganglia, and the developing brain during embryogenesis. [-]

ClinVar, ClinGen, MalaCards, KEGG Disease, DECIPHER, COSMIC, MARRVEL, GTR, DisGeNET, dbVAR, GHR, gnomAD