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XB-GENEPAGE-483794
???displayGene.symbol???: gdnf
???displayGene.name???: glial cell derived neurotrophic factor
???displayGene.synonyms???
gdnf-a
,
gdnf-b
,
hfb1-gdnf
(
???displayGene.geneFunction??? TGF-beta related peptide growth factor Protein Function
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Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake.
???displayGene.geneInteractants???
Human Physical (10), Co-citation (191)
Diseases: Disease Ontology: congenital central hypoventilation syndrome
MIM:
HIRSCHSPRUNG DISEASE, SUSCEPTIBILITY TO, 3; HSCR3
External Links:
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Gene ID & Location |
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Xenbase Gene ID
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XB-GENE-483795 | XB-GENE-865016 | XB-GENE-6464346 | |||||||||
Gene Symbol | gdnf | gdnf.L | gdnf.S | |||||||||
Chromosome | Chr1 | Chr1L | Chr1S | |||||||||
???displayGene.molecues??? | X. tropicalis | X. laevis.L | X. laevis.S | |||||||||
Genomic Sequence |
Version 10.0
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Version 10.1
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Version 10.1
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CDS |
CDS
Gene Model ![]() |
CDS
Gene Model ![]() |
CDS
Gene Model ![]() |
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Entrez Gene | 100498061 | 779087 | 100337571 | |||||||||
Ensembl Gene | gdnf (ENSXETG00000004782) | |||||||||||
mRNA |
NCBI Nt
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RefSeq
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RefSeq
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Protein
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NCBI Protein
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RefSeq
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RefSeq
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Reference Proteome |
F6UI64
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Q06PM8
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C7S813
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AlphaFold | View on AlphaFold | View on AlphaFold | View on AlphaFold | |||||||||
???displayGene.genomic???
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X. tropicalis | X. laevis.L | X. laevis.S | |||||||||
Genome Browser (Click image to open in interactive Genome Browser) |
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Genomic Synteny | Xenbase Simple Synteny Genomicus PANTHER | |||||||||||
???displayGene.expression??? | Development Stages Embryonic Tissues Adult Tissues | |||||||||||
Summary for
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More Information |
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Orthology
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???displayGene.human??? |
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???displayGene.mouse??? |
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rat |
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???displayGene.zebrafish??? |
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chicken |
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fruit fly |
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Publications | ||||||||||||
First |
GDNF signalling through the Ret receptor tyrosine kinase., Nature 1996 |
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Most Recent |
Isthmin-1: A critical regulator of branching morphogenesis and metanephric mesenchyme condensation during early kidney development., Bioessays 2024 |
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All | ???displayGene.papersAll??? 1 ???displayGene.omimPapers??? 1 ???displayGene.disOntPapers??? | |||||||||||
Functional Ontologies | X. tropicalis | X. laevis.L | X. laevis.S | |||||||||
GO | 8 terms | 22 terms | 7 terms | |||||||||
KEGG Pathways | Calcium signaling pathway | Calcium signaling pathway | Calcium signaling pathway | |||||||||
KOG | ||||||||||||
Reagents | X. tropicalis | X. laevis.L | X. laevis.S | |||||||||
CRISPRscan Tracks | gdnf | gdnf.L | gdnf.S | |||||||||
ORFs | gdnf ORF1 | |||||||||||
Clones | Horizon | Horizon | Horizon | |||||||||
Plasmids | Addgene.org | Addgene.org |
Symbol legend:
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