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XB-GENEPAGE-5850942
???displayGene.symbol???: birc5
???displayGene.name???: baculoviral IAP repeat-containing 5
???displayGene.synonyms???
api4
,
BIR1
,
birc5.1
,
birc5.1-a
,
birc5.1-b
,
epr-1
[+]
(
???displayGene.geneFunction??? apoptosis inhibitor Protein Function
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Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignme...[+]
???displayGene.geneInteractants???
Human Physical (1), Co-citation (318)
Diseases: External Links:
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Gene ID & Location |
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Xenbase Gene ID
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XB-GENE-5850943 | XB-GENE-5851077 | XB-GENE-6254428 | |||||||||
Gene Symbol | birc5 | birc5.L | birc5.S | |||||||||
Chromosome | Chr2 | Chr2L | Chr2S | |||||||||
???displayGene.molecues??? | X. tropicalis | X. laevis.L | X. laevis.S | |||||||||
Genomic Sequence |
Version 10.0
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Version 10.1
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Version 10.1
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CDS |
CDS
Gene Model ![]() |
CDS
Gene Model ![]() |
CDS
Gene Model ![]() |
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Entrez Gene | 733532 | 398418 | 394382 | |||||||||
Ensembl Gene | birc5 (ENSXETG00000004294) | |||||||||||
mRNA |
RefSeq
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RefSeq
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RefSeq
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Protein
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RefSeq
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RefSeq
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RefSeq
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Reference Proteome |
Q28H51
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Q4R1J6
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Q8JGN5
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AlphaFold | View on AlphaFold | View on AlphaFold | View on AlphaFold | |||||||||
???displayGene.genomic???
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X. tropicalis | X. laevis.L | X. laevis.S | |||||||||
Genome Browser (Click image to open in interactive Genome Browser) |
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Genomic Synteny | Xenbase Simple Synteny Genomicus PANTHER | |||||||||||
???displayGene.expression??? | Development Stages Embryonic Tissues Adult Tissues | |||||||||||
Summary for
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More Information |
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Proteomics | X. tropicalis | X. laevis.L | X. laevis.S | |||||||||
Embryonic Protein Expression | Stage profile: birc5.L![]() ![]() |
Stage profile: birc5.S![]() ![]() |
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Orthology
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???displayGene.human??? |
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???displayGene.mouse??? |
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rat |
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???displayGene.zebrafish??? |
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chicken |
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fruit fly |
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Publications | ||||||||||||
First |
Cloning and functional expression of the cDNA encoding an inwardly-rectifying potassium channel expressed in pancreatic beta-cells and in the brain., FEBS Lett 1995 |
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Most Recent |
Chromosomal passenger complex condensates generate parallel microtubule bundles in vitro., J Biol Chem 2024 ![]() |
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All | ???displayGene.papersAll??? 1 ???displayGene.morpholinoPapers??? | |||||||||||
Functional Ontologies | X. tropicalis | X. laevis.L | X. laevis.S | |||||||||
GO | 14 terms | 39 terms | 45 terms | |||||||||
KEGG Pathways | Apoptosis | Apoptosis | Apoptosis | |||||||||
KOG |
[DR] Apoptosis inhibitor IAP1 and related BIdomain proteins
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Reagents | X. tropicalis | X. laevis.L | X. laevis.S | |||||||||
CRISPRscan Tracks | birc5 | birc5.L | birc5.S | |||||||||
Antibodies | Birc5 Ab1 | Birc5 Ab1 | Birc5 Ab1 | |||||||||
ORFs | birc5.1.S ORF1, birc5.1.S ORF2 | |||||||||||
Clones | Horizon | Horizon | Horizon | |||||||||
Plasmids | Addgene.org | Addgene.org |
Symbol legend:
![](img/icons/rocket.gif)
![](img/icons/magnifying_glass.png)
![](img/icons/images.gif)
![](img/icons/info1.png)