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DOID:10652 - Alzheimer's disease
Disease Ontology Definition:A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.
Synonyms: AD, Alzheimer disease, Alzheimer disease, familial, Alzheimers dementia
Xenbase Genes
:
app,
ace,
paxip1,
nos3,
a2m,
psen1,
mpo,
apbb2,
apoe,
psen2,
adam10,
sorl1,
blmh,
pld3
| MONDO:0004975 - Alzheimer disease |
Other Model Organisms: Alliance, MGI, ZFIN, FlyBase, WormBase, RGD
Ontology Viewers: Disease Ontology, EMBL-EBI, OLSVis tree view, Ontobee
Parent(s):
tauopathy (is_a)