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XB-PHENO-16545

Xtr WT + dyrk1a CRISPR, Willsey HR et al. (2020)

Experiment + Assay: Xtr WT + dyrk1a CRISPR + NF35/36 (immunohistochemistry)
Background: Xtr.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
CRISPR dyrk1a dyrk1a
 NF stage 2 (2-cell) blastomere
Conditions:
Assay Type Assay Stages Antibody
immunohistochemistry NF stage 35 and 36 to NF stage 35 and 36 Tuba4b Ab5
Anatomical Phenotypes: abnormal brain morphology , abnormal telencephalon , decreased size of the telencephalon
Source: Fig. 2 F
Article: XB-ART-57038, PubMed