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XB-PHENO-16546

Xtr WT + dyrk1a CRISPR, Willsey HR et al. (2020)

Experiment + Assay: Xtr WT + dyrk1a CRISPR + NF46 (RNA-Seq)
Background: Xtr.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
CRISPR dyrk1a dyrk1a
NF stage 2 (2-cell) blastomere
Conditions:
Assay Type Assay Stages Antibody
RNA-Seq NF stage 46 to NF stage 46  
Expression Phenotypes (9):
increased amount aurkb expression in brain
increased amount ccna2 expression in brain
increased amount ccnb1.2 expression in brain
increased amount ccnb2 expression in brain
increased amount cdc45 expression in brain
increased amount cdca7 expression in brain
increased amount cdca8 expression in brain
increased amount cdk1 expression in brain
increased amount mcm4 expression in brain
Source: Fig. 3 D
Article: XB-ART-57038, PubMed