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XB-PHENO-16588

Xtr + pax9 MO, Farley-Barnes KI et al. (2020)

Experiment + Assay: Xtr + pax9 MO + NF18-19 (in situ hybridization)
Background: Xtr.Nigerian AKhok
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
morpholino injection pax9 MO1 pax9
 NF stage 1 whole organism
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization NF stage 18 to NF stage 19  
Anatomical Phenotypes: abnormal branchial crest , abnormal cell migration in neural crest , abnormal hyoid crest , abnormal mandibular crest
Expression Phenotypes (3):
decreased amount snai2 expression in cranial neural crest
decreased amount sox9 expression in cranial neural crest
decreased amount twist1 expression in cranial neural crest
Source: Fig. 6 B C
Article: XB-ART-57273, PubMed