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XB-PHENO-21166

Xla Wt + lhx8 MO + msx2 MO + BMS453, Kennedy AE and Dickinson AJ (2012)

Experiment + Assay: Xla Wt + lhx8 MO + msx2 MO + BMS453 + NF35/36 (morphology)
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
morpholino injection lhx8 MO1 lhx8.L
lhx8.S
 NF stage 1 blastomere
morpholino injection msx2 MO1 msx2.L
msx2.S
 NF stage 1 blastomere
chemical BMS 453
NF stage 24 whole organism
Conditions:
Assay Type Assay Stages Antibody
morphology NF stage 35 and 36  
Anatomical Phenotypes: abnormal roof of mouth morphology , decreased width of the craniofacial region
Source: fig.6.h
Article: XB-ART-44961, PubMed