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XB-PHENO-21244

Xla Wt + smurf1 + smurf2, Das S and Chang C (2012)

Experiment + Assay: Xla Wt + smurf1 + smurf2 + neurula stage (in situ hybridization)
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
mRNA injection smurf1.L smurf1.L
smurf1.S
 NF stage 1 blastomere
mRNA injection smurf2.S smurf2.S
smurf2.L
 NF stage 1 blastomere
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization neurula stage  
Expression Phenotypes (7):
mislocalised pax6.L expression in epidermis
increased amount pax6.L expression in epidermis
increased amount snai2.L expression in epidermis
mislocalised snai2.L expression in epidermis
decreased amount snai2.L expression in neural crest
mislocalised sox2.L expression in epidermis
increased amount sox2.L expression in epidermis
Source: fig.3.b
Article: XB-ART-45353, PubMed