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XB-PHENO-21252

Xla Wt + smurf1 + smurf2, Das S and Chang C (2012)

Experiment + Assay: Xla Wt + smurf1 + smurf2 + NF10.5 (in situ hybridization)
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
mRNA injection smurf1.L smurf1.L
smurf1.S
 NF stage 2 (2-cell) blastomere
mRNA injection smurf2.S smurf2.S
smurf2.L
 NF stage 2 (2-cell) blastomere
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization NF stage 10.5  
Expression Phenotypes (3):
decreased amount chrd.1.S expression in dorsal marginal zone
decreased amount tbxt.S expression in dorsal marginal zone
decreased amount wnt8a.L expression in ventro-lateral marginal zone
Source: fig.5.b
Article: XB-ART-45353, PubMed