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XB-PHENO-21323

Xla Wt + Mmu.lef1-Mmu.ctnnb1-GR + DEX, Steventon B and Mayor R (2012)

Experiment + Assay: Xla Wt + Mmu.lef1-Mmu.ctnnb1-GR + DEX + NF16 (in situ hybridization)
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
mRNA injection Tg(Mmu.lef1-Mmu.ctnnb1-GR) ctnnb1.S
ctnnb1.L
 NF stage 7 animal blastomere
chemical dexamethasone
NF stage 7 whole organism
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization NF stage 16  
Expression Phenotypes (1):
decreased amount sox2.L expression in neural plate
Source: fig.5.h, i
Article: XB-ART-45533, PubMed