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XB-PHENO-21563

Xla Wt + ptf1a-GR + DEX, Hanotel J et al. (2014)

Experiment + Assay: Xla Wt + ptf1a-GR + DEX + neurula stage (in situ hybridization)
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
mRNA injection Tg(ptf1a.L-GR) ptf1a.S
ptf1a.L
 NF stage 2 (2-cell) blastomere
chemical dexamethasone
NF stage 12.5 whole organism
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization neurula stage  
Expression Phenotypes (4):
mislocalised prdm13.L expression in ectoderm
increased amount prdm13.L expression in ectoderm
increased amount prdm13.L expression in neural plate
mislocalised prdm13.L expression in pre-chordal neural plate
Source: A
Article: XB-ART-48401, PubMed