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XB-PHENO-21583

Xla Wt + ptf1a + rbpj, Hanotel J et al. (2014)

Experiment + Assay: Xla Wt + ptf1a + rbpj + neurula stage (in situ hybridization)
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
mRNA injection ptf1a.L ptf1a.S
ptf1a.L
 NF stage 2 (2-cell) blastomere
mRNA injection rbpj.L rbpj.S
rbpj.L
 NF stage 2 (2-cell) blastomere
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization neurula stage  
Expression Phenotypes (4):
mislocalised neurog2.L expression in neural tube
increased amount neurog2.L expression in neural tube
mislocalised prdm13.L expression in neural plate
increased amount prdm13.L expression in neural plate
Source: C, D
Article: XB-ART-48401, PubMed