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XB-PHENO-21720

Xla Wt + dnsnai2, Wylie LA et al. (2015)

Experiment + Assay: Xla Wt + dnsnai2 + NF17-18 (in situ hybridization)
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
mRNA injection Tg(dnsnai2) snai2.S
snai2.L
 NF stage 2 (2-cell) blastomere
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization NF stage 17 to NF stage 18  
Anatomical Phenotypes: abnormal cell migration in neural crest
Expression Phenotypes (1):
decreased amount hand2.L expression in anterior neural ridge
Source: Fig.1.a,b
Article: XB-ART-50246, PubMed