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XB-PHENO-21877

Xla Wt + dnhes4-GR + DEX, Vega-López GA et al. (2015)

Experiment + Assay: Xla Wt + dnhes4-GR + DEX + NF21-22 (in situ hybridization)
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
mRNA injection Tg(dnhes4.S-GR) hes4.L
hes4.S
 NF stage 4 (8-cell) blastomere
chemical dexamethasone
NF stage 20 whole organism
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization NF stage 21 to NF stage 22  
Anatomical Phenotypes: abnormal cell migration in neural crest
Expression Phenotypes (1):
decreased amount snai2.L expression in cranial neural crest
Source: fig.11.b
Article: XB-ART-50752, PubMed