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XB-PHENO-22396

Xla Wt + Hsa.sfrp2, Brinkmann EM et al. (2016)

Experiment + Assay: Xla Wt + Hsa.sfrp2 + NF32 (morphology)
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
mRNA injection Tg(Hsa.sfrp2) sfrp2.L
sfrp2.S
 NF stage 3 (4-cell) blastomere
Conditions:
Assay Type Assay Stages Antibody
morphology NF stage 32  
Anatomical Phenotypes: abnormal incomplete closing of the neural tube , abnormal neural tube closure , decreased length of anterior-posterior axis
Source: fig.1.a
Article: XB-ART-52034, PubMed