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XB-PHENO-22413

Xla Wt + dse MO, Gouignard N et al. (2016)

Experiment + Assay: Xla Wt + dse MO + NF20 (in situ hybridization)
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
morpholino injection dse MO1 dse.L
dse.S
 NF stage 2 (2-cell) animal pole
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization NF stage 20  
Anatomical Phenotypes: abnormal cell migration , abnormal migratory neural crest cell
Expression Phenotypes (1):
decreased amount twist1 expression in premigratory neural crest cell
Human Disease Associations: Ehlers-Danlos syndrome
Source: Fig.5 B
Article: XB-ART-52061, PubMed