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XB-PHENO-22906

Xla Wt + lhx1 + otx2 + sia1 MO + sia2 MO, Rankin SA et al. (2011)

Experiment + Assay: Xla Wt + lhx1 + otx2 + sia1 MO + sia2 MO + NF11 (in situ hybridization)
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
morpholino injection sia1 MO1 sia1.L
sia1.S
 NF stage 3 (4-cell) blastomere
morpholino injection sia2 MO1 sia2.S
sia2.L
 NF stage 3 (4-cell) blastomere
mRNA injection otx2.L otx2.L
otx2.S
 NF stage 4 (8-cell) blastomere D2
mRNA injection lhx1.L lhx1.L
lhx1.S
 NF stage 4 (8-cell) blastomere D2
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization NF stage 11  
Expression Phenotypes (2):
increased amount gsc.L expression in dorsal endomesoderm
decreased amount hhex.L expression in dorsal endoderm
Source: fig.7.c
Article: XB-ART-42631, PubMed