XB-PHENO-22907
Xla Wt + lhx1 + otx2, Rankin SA et al. (2011)
Experiment + Assay: |
Xla Wt + lhx1 + otx2 +
NF11 (in situ hybridization)
|
Manipulations: |
Manipulation Type |
Reagent |
Target Gene |
Stage |
Treatment Area |
mRNA injection
|
otx2.L
|
otx2.L
otx2.S
|
NF stage 4 (8-cell)
|
blastomere V2
|
mRNA injection
|
lhx1.L
|
lhx1.L
lhx1.S
|
NF stage 4 (8-cell)
|
blastomere V2
|
|
Conditions: |
Assay Type |
Assay Stages |
Antibody |
in situ hybridization
|
NF stage 11
|
|
|
|
Expression Phenotypes (7):
|
increased amount
gsc.L
expression in dorsal endomesoderm
|
increased amount
gsc.L
expression in ventral endoderm
|
mislocalised
gsc.L
expression in ventral endoderm
|
increased amount
hhex.L
expression in dorsal endoderm
|
mislocalised
hhex.L
expression in ventral endoderm
|
increased amount
hhex.L
expression in ventral endoderm
|
increased amount
otx2.L
expression in ventral endoderm
|
|