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XB-PHENO-22931

Xla Wt + lhx1 MO + otx2 MO, Rankin SA et al. (2011)

Experiment + Assay: Xla Wt + lhx1 MO + otx2 MO + NF33/34-35 and 36 (morphology)
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
morpholino injection otx2 MO1 otx2.L
otx2.S
 NF stage 2 (2-cell) blastomere
morpholino injection lhx1 MO1 lhx1.L
lhx1.S
 NF stage 2 (2-cell) blastomere
Conditions:
Assay Type Assay Stages Antibody
morphology NF stage 33 and 34 to NF stage 35 and 36  
Anatomical Phenotypes: abnormal embryo morphology , abnormal gastrulation
Source: fig.S1
Article: XB-ART-42631, PubMed