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XB-PHENO-23057

Xtr Wt + Mmu.osr1-GR + DEX, Rankin SA et al. (2012)

Experiment + Assay: Xtr Wt + Mmu.osr1-GR + DEX + NF42 (in situ hybridization)
Background: Xtr.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
mRNA injection Tg(Mmu.osr1-GR) osr1
NF stage 4 (8-cell) blastomere
chemical dexamethasone
NF stage 20 whole organism
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization NF stage 42  
Expression Phenotypes (6):
decreased amount bmp4 expression in intermediate mesoderm
decreased amount bmp4 expression in pharyngeal mesenchyme
decreased amount hand1 expression in intermediate mesoderm
decreased amount hand1 expression in pharyngeal mesenchyme
decreased amount msx1 expression in head
decreased amount msx1 expression in pharyngeal mesenchyme
Source: fig.7.a
Article: XB-ART-45616, PubMed