Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.
XB-PHENO-23074

Xla Wt + fzd7 MO, Zhang Z et al. (2013)

Experiment + Assay: Xla Wt + fzd7 MO + NF35/36 (in situ hybridization)
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
morpholino injection fzd7 MO3 fzd7.L
fzd7.S
 NF stage 6 (32-cell) dorsal animal hemisphere blastomere
morpholino injection fzd7 MO5 fzd7.L
fzd7.S
 NF stage 6 (32-cell) dorsal animal hemisphere blastomere
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization NF stage 35 and 36  
Anatomical Phenotypes: abnormal head morphology , obsolete abnormally edematous pharyngeal region
Expression Phenotypes (3):
decreased amount nr1h5.L expression in liver
decreased amount pdx1.L expression in duodenum
decreased amount pdx1.L expression in pancreas
Source: fig.2.i
Article: XB-ART-46881, PubMed