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XB-PHENO-23153

Xla Wt + Mmu.fgfr1del-Mmu.fkbp1adel + B/B Homodimerizer, Shifley ET et al. (2012)

Experiment + Assay: Xla Wt + Mmu.fgfr1del-Mmu.fkbp1adel + B/B Homodimerizer + NF35/36 (in situ hybridization)
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
mRNA injection Tg(Mmu.fgfr1del-Mmu.fkbp1adel) fgfr1.L
fgfr1.S
 NF stage 3 (4-cell) dorsal vegetal hemisphere blastomere
chemical B/B Homodimerizer
NF stage 18 whole organism
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization NF stage 35 and 36  
Expression Phenotypes (1):
increased amount hhex.L expression in liver
Source: fig.3.a,c,d
Article: XB-ART-45962, PubMed