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XB-PHENO-23395

Xla Wt + epha4 MO, Rothe M et al. (2017)

Experiment + Assay: Xla Wt + epha4 MO + NF42 (in situ hybridization)
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
morpholino injection epha4 MO1 epha4.L
epha4.S
 NF stage 4 (8-cell) blastomere
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization NF stage 42  
Anatomical Phenotypes: abnormal development of retinal layer , abnormally localised retinal inner nuclear layer
Expression Phenotypes (7):
increased amount pax6.L expression in amacrine cell
increased amount pax6.L expression in retinal ganglion cell layer
mislocalised pax6.L expression in retinal inner nuclear layer
increased amount pou4f1.L expression in retinal ganglion cell layer
decreased amount rho.L expression in photoreceptor layer
mislocalised rho.L expression in retinal inner nuclear layer
increased amount vsx1.L expression in retinal inner nuclear layer
Source: fig.S2.a
Article: XB-ART-52888, PubMed