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XB-PHENO-23677

Xla Wt + Nf2 MO, Zhu X et al. (2015)

Experiment + Assay: Xla Wt + Nf2 MO + NF23-24 (in situ hybridization)
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
morpholino injection Nf2 MO1 nf2.S
nf2.L
 NF stage 4 (8-cell) blastomere
morpholino injection Nf2 MO2 nf2.S
nf2.L
 NF stage 4 (8-cell) blastomere
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization NF stage 23 to NF stage 24  
Expression Phenotypes (4):
increased amount hoxc9-like.L expression in spinal cord
mislocalised hoxc9-like.L expression in spinal cord
decreased amount six3.L expression in retinal neural layer
mislocalised six3.L expression in retinal neural layer
Source: fig.3.d
Article: XB-ART-51212, PubMed