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XB-PHENO-23753

Xla Wt + dnbmpr1a + sia1 MO + sia2 MO, Rankin SA et al. (2011)

Experiment + Assay: Xla Wt + dnbmpr1a + sia1 MO + sia2 MO + NF11 (in situ hybridization)
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
morpholino injection sia1 MO1 sia1.L
sia1.S
 NF stage 3 (4-cell) blastomere
morpholino injection sia2 MO1 sia2.S
sia2.L
 NF stage 3 (4-cell) blastomere
mRNA injection Tg(dnbmpr1a) bmpr1a.S
bmpr1a.L
 NF stage 4 (8-cell) blastomere D2
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization NF stage 11  
Expression Phenotypes (6):
decreased amount chrd.1.L expression in dorsal endoderm
decreased amount hhex.L expression in dorsal endoderm
decreased amount ventx1.2.L expression in dorsal endoderm
increased amount ventx1.2.L expression in ventral endoderm
decreased amount ventx2.2.L expression in dorsal endoderm
increased amount ventx2.2.L expression in ventral endoderm
Source: fig.8
Article: XB-ART-42631, PubMed