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XB-PHENO-23773

Xtr Wt + osr1 MO + osr2 MO, Rankin SA et al. (2012)

Experiment + Assay: Xtr Wt + osr1 MO + osr2 MO + NF35/36 (immunohistochemistry)
Background: Xtr.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
morpholino injection osr1 MO1 osr1
 NF stage 4 (8-cell) blastomere
morpholino injection osr2 MO1 osr2
 NF stage 4 (8-cell) blastomere
Conditions:
Assay Type Assay Stages Antibody
immunohistochemistry NF stage 35 and 36  
Anatomical Phenotypes: abnormal development of foregut , abnormal development of lung
Expression Phenotypes (3):
decreased amount fn1 expression in lung bud
increased amount smad1 expression in dorsal foregut
increased amount smad1 expression in lung bud
Source: fig.S7.a
Article: XB-ART-45616, PubMed