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XB-PHENO-23810

Xtr wt + Equs RAPGEF5 mRNA, Rivas VN et al. (2020)

Experiment + Assay: Xtr wt + Equs RAPGEF5 mRNA + NF 29 & 30
Background: Xtr.Nigerian AKhok
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
mRNA injection   rapgef5
 NF stage 2 (2-cell) right blastomere
Conditions:
Assay Type Assay Stages Antibody
whole-mount microscopy NF stage 29 and 30 to NF stage 29 and 30  
Anatomical Phenotypes: abnormal axis elongation , abnormal incomplete closing of the blastopore , abnormal incomplete closing of the neural tube , absent head , absent tail
Human Disease Associations: hypoparathyroidism
Source: Fig. 5 C D
Article: XB-ART-57396, PubMed