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XB-PHENO-23815

Xtr wt + nup188 MO + nup205 MO, Marquez J et al. (2021)

Experiment + Assay: Xtr wt + nup188 MO + nup205 MO + NF 28
Background: Xtr.Nigerian AKhok
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
morpholino injection nup188 MO1 nup188
 NF stage 2 (2-cell) blastomere
morpholino injection nup205 MO1 nup205
 NF stage 2 (2-cell) blastomere
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization NF stage 28 to NF stage 28  
transmission electron microscopy NF stage 28 to NF stage 28  
Anatomical Phenotypes: abnormally localised basal body , abnormal multiciliated cell
Human Disease Associations: ciliopathy
Source: Fig. 3 B r2c2, r2c3
Article: XB-ART-57453, PubMed