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XB-PHENO-23838

Xla Wt + neurog3-GR + DEX, Oropeza D and Horb M (2012)

Experiment + Assay: Xla Wt + neurog3-GR + DEX + NF32 (in situ hybridization)
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
mRNA injection Tg(neurog3.S-GR) neurog3.S
neurog3.L
 NF stage 4 (8-cell) vegetal blastomere
chemical dexamethasone
NF stage 12 whole organism
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization NF stage 32  
Anatomical Phenotypes: abnormal type B pancreatic cell differentiation
Expression Phenotypes (1):
increased amount pax4.L expression in dorsal pancreatic bud
Source: Fig 5 c
Article: XB-ART-44499, PubMed