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XB-PHENO-23910

Xla Wt + six1-V17E, Shah AM et al. (2020)

Experiment + Assay: Xla Wt + six1-V17E + NF28-32 (in situ hybridization)
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
mRNA injection Tg(six1-V17E) six1 (Xla)
 NF stage 8 animal blastomere
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization NF stage 28 to NF stage 32  
Expression Phenotypes (1):
decreased amount irx1.L expression in otic vesicle
Human Disease Associations: branchiootic syndrome, branchiootorenal syndrome
Source: Fig. 4 B
Article: XB-ART-56645, PubMed