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XB-PHENO-23952

Xla Wt + Six1-Y129C, Shah AM et al. (2020)

Experiment + Assay: Xla Wt + Six1-Y129C + NF46-47 (3D imaging)
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
mRNA injection Tg(six1-Y129C) six1 (Xla)
 NF stage 4 (8-cell) animal blastomere
Conditions:
Assay Type Assay Stages Antibody
3D imaging NF stage 46 to NF stage 47  
Anatomical Phenotypes: decreased size of the lateral semicircular canal
Human Disease Associations: branchiootic syndrome, branchiootorenal syndrome
Source: Fig. S 1 E
Article: XB-ART-56645, PubMed